KCTD7 antibody (AA 112-180)

Catalog No. ABIN1387694

The Rabbit Polyclonal anti-KCTD7 antibody is suitable to detect KCTD7 in samples from Human. It has been validated for WB, ELISA, FACS, ICC, IF (cc), IF (p), IHC (fro) and IHC (p).

Quick Overview for KCTD7 antibody (AA 112-180) (ABIN1387694)

Target: KCTD7 (Potassium Channel Tetramerisation Domain Containing 7 (KCTD7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCTD7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-KCTD7 Antibody

Binding Specificity: AA 112-180

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human KCTD7

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for KCTD7

Target: KCTD7 (Potassium Channel Tetramerisation Domain Containing 7 (KCTD7))

Alternative Name: KCTD7

Background:

Synonyms: BTB/POZ domain containing protein KCTD7, EPM3, FLJ32069, Potassium channel tetramerisation domain containing 7, KCTD7_HUMAN.

Background: Epilepsy affects about 0.5 % of the world?s population and has a large genetic component. Epilepsy results from an electrical hyperexcitability in the central nervous system. Potassium channels are important regulators of electrical signaling, determining the firing properties and responsiveness of a variety of neurons. Benign familial neonatal convulsions (BFNC), an autosomal dominant epilepsy of infancy, has been shown to be caused by mutations in the KCNQ2 or the KCNQ3 potassium channel genes. KCNQ2 and KCNQ3 are voltage-gated potassium channel proteins with six putative transmembrane domains. Both proteins display a broad distribution within the brain, with expression patterns that largely overlap.

Gene ID: 154881

UniProt: Q96MP8