Musashi 1/2 (AA 66-150) antibody

Catalog No. ABIN1387744

This Rabbit Polyclonal antibody specifically detects Musashi 1/2 in ICC, IF (cc), IF (p), IHC (fro) and IHC (p). It exhibits reactivity toward Mouse and Rat.

Quick Overview for Musashi 1/2 (AA 66-150) antibody (ABIN1387744)

Target: Musashi 1/2

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Application: Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details

Binding Specificity: AA 66-150

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Cow,Pig,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Musashi 1

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details

Target: Musashi 1/2

Background:

Synonyms: Msi 1, Msi1, Msi-1, MSI1H_HUMAN, Musashi homolog 1, Musashi-1, Musashi1, Musashi 1, RNA binding protein Musashi homolog 1, RNA-binding protein Musashi homolog 1, Msi 2, Msi2, Msi-2, MSI2H_HUMAN, Musashi homolog 2, Musashi-2, Musashi2, Musashi 2, RNA binding protein Musashi homolog 2, RNA-binding protein Musashi homolog 2.

Background: Musashi1 (Msi1) is an RNA-binding protein expressed in neural progenitor cells and neural stem cells. Msi1 is the mammalian homolog of Drosophila Musashi. The gene encoding human Msi1 encodes a 362 amino acid protein. In murine embryonic neural progenitor cells, Msi1 localizes to the cytoplasm and is downregulated during differentiation. Msi1 binds to NUMB, which encodes a membrane-associated antagonist of Notch signaling. Msi1 appears to function in the proliferation and maintenance of stem cell populations of the central nervous system. In addition to its usefulness as a marker for neural progenitor cells in normal human brains, Msi1 is also a marker for human gliomas. In rats, Msi1 is expressed in Sertoli cells of the testis and granulosa cells of the ovary.

Gene ID: 4440, 124540