Contactin 5 antibody (AA 801-900)

Catalog No. ABIN1387811

The Rabbit Polyclonal anti-Contactin 5 antibody has been validated for ELISA, WB, ICC, IF (cc), IF (p), IHC (fro) and IHC (p). It is suitable to detect Contactin 5 in samples from Human.

Quick Overview for Contactin 5 antibody (AA 801-900) (ABIN1387811)

Target: Contactin 5 (CNTN5)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Contactin 5 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Contactin 5 Antibody

Binding Specificity: AA 801-900

Predicted Reactivity: Human,Mouse,Rat,Dog,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Contactin 5

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for Contactin 5

Target: Contactin 5 (CNTN5)

Alternative Name: CNTN5/Contactin 5

Background:

Synonyms: Contactin5, Contactin-5, hNB 2, HNB 2s, NB 2, Neural recognition molecule NB 2, CNTN5_HUMAN.

Background: Changes in synaptic efficacy can mediate crucial processes during learning and memory formation. Accumulating evidence implicates cell adhesion molecules in activity-dependent synaptic modifications associated with paired-pulse facilitation (PPF), long-term potentiation (LTP) and long-term depression (LTD). Among the cell adhesion molecules involved in these processes are the contactins. Contactins are immunoglobulin superfamily members that play a selective role in synaptic plasticity, PPF and LTD, and may regulate cell-cell interactions contributing to synaptic plasticity in conjunction with other synapse targeting molecules, including paranodin and phosphacan. In addition, contactins are essential components that control expression and distribution of Na+ channels in neurons, junctional attachment at the paranode, and ultimately the physiology of the myelinated nerve. The human Contactin 1 gene encodes a 1,018 amino acid protein. The human Contactin 3 gene encodes a 646 amino acid plasmacytoma-associated neuronal glycoprotein. The human Contactin 5 gene encodes a 1,100 amino acid neural adhesion molecule. The human Contactin 6 gene encodes a 1,028 amino acid neural adhesion molecule.

Gene ID: 53942

Pathways: Sensory Perception of Sound