GBA antibody
Quick Overview for GBA antibody (ABIN1387836)
Target
See all GBA AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purification
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human Acid beta-glucosidase
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Isotype
- IgG
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Application Notes
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WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C
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Expiry Date
- 12 months
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- GBA (Glucosidase, Beta, Acid (GBA))
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Alternative Name
- GBA/Acid beta-Glucosidase
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Background
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Beta-Glucosidase is a predominantly liver enzyme which efficiently hydrolyzes Beta-D-glucoside and Beta-D-galactoside. Defects in Beta-Glucosidase cause Gaucher disease, an inherited condition distinguished by the accumulation of glucosylceramide within the cells of the reticuloendothelial system. Beta-Glucosidase is used in enzyme replacement treatment aimed at treating Gaucher disease. The absorption of dietary flavonoid glycosides in humans involves a critical deglycosylation step that is mediated by epithelial Beta-glucosidases.
Synonyms: Acid beta glucosidase, Acid beta-glucosidase, Alglucerase, Beta glucocerebrosidase, BETA GLUCOSIDASE, ACID, Beta-glucocerebrosidase, betaGC, D glucosyl N acylsphingosine glucohydrolase, D-glucosyl-N-acylsphingosine glucohydrolase, EC 3.2.1.45 , GBA, Gba protein, GBA1, GC antibody GCase, GCB, GLCM_HUMAN, GLUC, Glucocerebrosidase alt., Glucocerebrosidase, GLUCOCEREBROSIDASE PSEUDOGENE, Glucosidase beta, Glucosidase, beta, acid, Glucosidase, beta, acid includes glucosylceramidase, Glucosylceramidase, Imiglucerase, Lysosomal glucocerebrosidase.
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Pathways
- Cellular Glucan Metabolic Process
Target
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