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GBA antibody

This anti-GBA antibody is a Rabbit Polyclonal antibody detecting GBA in WB, IHC (p) and IF (p). Suitable for Human, Mouse and Rat.
Catalog No. ABIN1387836

Quick Overview for GBA antibody (ABIN1387836)

Target

See all GBA Antibodies
GBA (Glucosidase, Beta, Acid (GBA))

Reactivity

  • 75
  • 45
  • 33
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Mouse, Rat

Host

  • 92
  • 12
Rabbit

Clonality

  • 84
  • 20
Polyclonal

Conjugate

  • 45
  • 20
  • 12
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This GBA antibody is un-conjugated

Application

  • 73
  • 41
  • 26
  • 24
  • 13
  • 10
  • 10
  • 9
  • 5
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Purification

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human Acid beta-glucosidase

    Isotype

    IgG
  • Application Notes

    WB 1:100-1000
    IHC-P 1:100-500
    IF(IHC-P) 1:50-200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C

    Expiry Date

    12 months
  • Target

    GBA (Glucosidase, Beta, Acid (GBA))

    Alternative Name

    GBA/Acid beta-Glucosidase

    Background

    Beta-Glucosidase is a predominantly liver enzyme which efficiently hydrolyzes Beta-D-glucoside and Beta-D-galactoside. Defects in Beta-Glucosidase cause Gaucher disease, an inherited condition distinguished by the accumulation of glucosylceramide within the cells of the reticuloendothelial system. Beta-Glucosidase is used in enzyme replacement treatment aimed at treating Gaucher disease. The absorption of dietary flavonoid glycosides in humans involves a critical deglycosylation step that is mediated by epithelial Beta-glucosidases.

    Synonyms: Acid beta glucosidase, Acid beta-glucosidase, Alglucerase, Beta glucocerebrosidase, BETA GLUCOSIDASE, ACID, Beta-glucocerebrosidase, betaGC, D glucosyl N acylsphingosine glucohydrolase, D-glucosyl-N-acylsphingosine glucohydrolase, EC 3.2.1.45 , GBA, Gba protein, GBA1, GC antibody GCase, GCB, GLCM_HUMAN, GLUC, Glucocerebrosidase alt., Glucocerebrosidase, GLUCOCEREBROSIDASE PSEUDOGENE, Glucosidase beta, Glucosidase, beta, acid, Glucosidase, beta, acid includes glucosylceramidase, Glucosylceramidase, Imiglucerase, Lysosomal glucocerebrosidase.

    Pathways

    Cellular Glucan Metabolic Process
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