G Protein-Coupled Receptor 116 antibody (AA 501-600)

Catalog No. ABIN1387839

This anti-G Protein-Coupled Receptor 116 antibody is a Rabbit Polyclonal antibody detecting G Protein-Coupled Receptor 116 in ELISA, IHC (p), ICC, IF (cc), IF (p) and IHC (fro). Suitable for Human.

Quick Overview for G Protein-Coupled Receptor 116 antibody (AA 501-600) (ABIN1387839)

Target: G Protein-Coupled Receptor 116 (GPR116)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This G Protein-Coupled Receptor 116 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-G Protein-Coupled Receptor 116 Antibody

Binding Specificity: AA 501-600

Predicted Reactivity: Human,Mouse,Rat,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human G protein coupled receptor 116

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for G Protein-Coupled Receptor 116

Target: G Protein-Coupled Receptor 116 (GPR116)

Alternative Name: GPR116

Background:

Synonyms: DKFZp564O1923, FLJ90640, G protein coupled receptor 116, G protein coupled receptor 116, GP116_HUMAN, GPR116, Ig Hepta homolog, KIAA0758, KIAA0758, KPG_001, OTTHUMP00000016557, Probable G protein coupled receptor 116, Probable G-protein coupled receptor 116_ GPCR GPR116.

Background: G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR116 (G protein-coupled receptor 116) is a 1,346 amino acid multi-pass membrane protein that contains one SEA domain, one GPS domain and three Ig-like domains and belongs to the GPR family. Existing as a dilsulfide-liked homodimer at the cell surface, GPR116 exists as multiple alternatively spliced isoforms and is thought to play a role in regulating and maintaining proper acid-base balance throughout the cell.

Pathways: Carbohydrate Homeostasis