CABP1 antibody (AA 311-355)

Catalog No. ABIN1387876

This Rabbit Polyclonal antibody specifically detects CABP1 in ELISA, IHC (p), ICC, IF (cc), IF (p) and IHC (fro). It exhibits reactivity toward Mouse.

Quick Overview for CABP1 antibody (AA 311-355) (ABIN1387876)

Target: CABP1 (Calcium Binding Protein 1 (CABP1))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CABP1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-CABP1 Antibody

Binding Specificity: AA 311-355

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CABP1

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for CABP1

Target: CABP1 (Calcium Binding Protein 1 (CABP1))

Alternative Name: CABP1

Background:

Synonyms: CABP 1, CABP1, CABP-1, CABP1_HUMAN, Calbrain, Calcium binding protein 1, Calcium binding protein 5, Calcium-binding protein 1, Caldendrin, HCALB BR, HCALB_BR.

Background: Calcium plays an essential role in many biological processes. The calcium binding protein (CaBP) family shares much similarity to calmodulin. It has been shown that CaBP proteins can substitute functionally for, and probably augment the function of, calmodulin. Calcium binding proteins are a crucial part of calcium mediated cellular signal transduction in the central nervous system. There are several members of the family with varying expression patterns. CaBP1 and CaBP2 can be expressed as multiple, alternatively spliced variants in brain and retina. CaBP3, CaBP4 and CaBP 5 are restricted to retinal rod and cone cells. CaBP7 shares 70 % homology with CaBP8 and 50 % homology with CaM I.

Pathways: Synaptic Membrane, Negative Regulation of Transporter Activity