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STXBP6 antibody (AA 1-100) (Biotin)

STXBP6 Reactivity: Human WB, ELISA, IHC (p), IHC (fro) Host: Rabbit Polyclonal Biotin
Catalog No. ABIN1388911
  • Target See all STXBP6 Antibodies
    STXBP6 (Syntaxin Binding Protein 6 (Amisyn) (STXBP6))
    Binding Specificity
    • 14
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 4
    AA 1-100
    Reactivity
    • 44
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 43
    • 1
    Rabbit
    Clonality
    • 44
    Polyclonal
    Conjugate
    • 12
    • 6
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This STXBP6 antibody is conjugated to Biotin
    Application
    • 33
    • 21
    • 13
    • 13
    • 7
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Predicted Reactivity
    Human,Mouse,Rat,Cow,Sheep,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Amisyn
    Isotype
    IgG
    Top Product
    Discover our top product STXBP6 Primary Antibody
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C for 12 months.
    Expiry Date
    12 months
  • Target
    STXBP6 (Syntaxin Binding Protein 6 (Amisyn) (STXBP6))
    Alternative Name
    Amisyn (STXBP6 Products)
    Synonyms
    MGC68796 antibody, zgc:86678 antibody, wu:fd20e06 antibody, amisyn antibody, hspc156 antibody, MGC88977 antibody, STXBP6 antibody, LOC100226852 antibody, BC024598 antibody, C85317 antibody, Amisyn antibody, syntaxin binding protein 6 L homeolog antibody, syntaxin binding protein 6 (amisyn) antibody, syntaxin binding protein 6 antibody, stxbp6.L antibody, stxbp6 antibody, STXBP6 antibody, Stxbp6 antibody
    Background

    Synonyms: Amisyn, HSPC156, STXB6_HUMAN, STXBP6, Syntaxin binding protein 6, Syntaxin-binding protein 6.

    Background: Amisyn is a mostly cytosolic protein related to Tomosyn which plays an important role in SNARE complex assembly. Amisyn contains a v-SNARE coiled coil homology domain that binds to Syntaxin 1A and weakly to Syntaxin 4. Three isoforms exist for Amisyn. Isoform 1 is the full length protein, isoform 2 has a different amino acid sequence between residues 204-210 and isoform 3 is missing amino acids 1-102 and contains a different sequence for amino acids 103-150. Amisyn lacks a transmembrane domain and therefore is unable to assemble into a functional, membrane-anchored SNARE complex. This suggests that Amisyn may instead be acting to maintain SNARE conformation and facilitate the binding of VAMP-2. Amisyn can inhibit exocytosis independent of Syntaxin binding.

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