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TCF12 antibody (AA 51-150) (Biotin)

This Rabbit Polyclonal antibody specifically detects TCF12 in WB, ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Human and Rat.
Catalog No. ABIN1390087
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$383.42
$451.08
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100 μL
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Quick Overview for TCF12 antibody (AA 51-150) (Biotin) (ABIN1390087)

Target

See all TCF12 Antibodies
TCF12 (Transcription Factor 12 (TCF12))

Reactivity

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  • 9
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  • 2
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Human, Rat

Host

  • 46
  • 3
Rabbit

Clonality

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Polyclonal

Conjugate

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  • 1
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  • 1
  • 1
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This TCF12 antibody is conjugated to Biotin

Application

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  • 1
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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Binding Specificity

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    • 1
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    AA 51-150

    Cross-Reactivity

    Human, Rat

    Predicted Reactivity

    Mouse,Sheep,Horse,Rabbit,Zebrafish

    Purification

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human TCF12

    Isotype

    IgG
  • Application Notes

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C for 12 months.

    Expiry Date

    12 months
  • Target

    TCF12 (Transcription Factor 12 (TCF12))

    Alternative Name

    TCF12/HEB

    Background

    Synonyms: bHLHb20, Class B basic helix-loop-helix protein 20, DNA binding protein HTF4, DNA-binding protein HTF4, E box binding protein, E-box-binding protein, HEB, HTF4, HTF4_HUMAN, TCF-12, Tcf12, Transcription factor 12, Transcription factor HTF-4, Transcription factor HTF4.

    Background: Differentiation of myogenic cells is regulated by multiple positively and negatively acting factors. One well characterized family of helix-loop-helix (HLH) proteins known to play an important role in the regulation of muscle cell development includes Myo D, myogenin, Myf-5 and Myf-6 (also designated MRF-4 or herculin). Myo D transcription factors form heterodimers with products of a more widely expressed family of bHLH genes, the E family, which consists of at least three distinct genes: E2A, IF2 and HEB. Myo D-E heterodimers bind avidly to consensus (CANNTG) E box target sites that are functionally important elements in the upstream regulatory sequences of many muscle-specific terminal differentiation genes. Both homo- and hetero-oligomers of these proteins are able to distinguish very closely related E box proteins and are believed to play important roles in lineage specific gene expression.

    Gene ID

    6938

    UniProt

    Q99081

    Pathways

    SARS-CoV-2 Protein Interactome
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