Rim1/Abca4 (AA 751-850) antibody (AbBy Fluor® 647)

Catalog No. ABIN1390788

The AbBy Fluor® 647-conjugated Rabbit Polyclonal anti-Rim1/Abca4 antibody (ABIN1390788) specifically detects Rim1/Abca4 in WB, IF (cc) and IF (p). The antibody is reactive with Human samples.

Quick Overview for Rim1/Abca4 (AA 751-850) antibody (AbBy Fluor® 647) (ABIN1390788)

Target: Rim1/Abca4

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: AbBy Fluor® 647

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details

Binding Specificity: AA 751-850

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RIM1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: Rim1/Abca4

Background:

Synonyms: ABCA4, CORD7, Rab-3-interacting molecule 1, Rab-3-interacting protein 2, RAB3 interacting protein 2, Rab3-interacting molecule 1, Rab3ip1, RAB3IP2, Regulating synaptic membrane exocytosis 1, Regulating synaptic membrane exocytosis protein 1, RIM 1, RIM, Rims1 gene name, RIMS1, RIMS1_HUMAN, Serg1 gene name, KIAA0340, MGC167823, MGC176677, Nbla00761.

Background: The protein encoded by this gene is a RAS gene superfamily member that regulates synaptic vesicle exocytosis. This gene also plays a role in the regulation of voltage-gated calcium channels during neurotransmitter and insulin release. Mutations have suggested a role cognition and have been identified as the cause of cone-rod dystrophy type 7. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Mar 2012].