VAX2 antibody (AA 131-205) (Biotin)

Catalog No. ABIN1391617

This Rabbit Polyclonal antibody specifically detects VAX2 in WB, ELISA, IHC (fro) and IHC (p). It exhibits reactivity toward Human.

Quick Overview for VAX2 antibody (AA 131-205) (Biotin) (ABIN1391617)

Target: VAX2 (Ventral Anterior Homeobox 2 (VAX2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VAX2 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-VAX2 Antibody (Biotin)

Binding Specificity: AA 131-205

Predicted Reactivity: Human,Mouse,Rat,Cow,Sheep,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human VAX2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for VAX2

Target: VAX2 (Ventral Anterior Homeobox 2 (VAX2))

Alternative Name: VAX2

Background:

Synonyms: DRES93, Ventral anterior homeobox 2, VAX2_HUMAN.

Background: VAX2 is a 290 amino acid homeobox protein that plays a crucial role in development of the eye, particularly in the specification of the ventral optic vesicle and in establishment of a correct dorsoventral pattern. VAX2 acts as a transcription factor with VAX1 to cooperatively regulate retinal differentiation, neuroepithelial cell proliferation and axial polarization in the retina. Together, VAX1 and VAX2 repress transcription of Pax-6, a strong inducer of retinal development. VAX1 and VAX2 localize to the nucleus and contain one homeobox DNA-binding domain each.