VAX2 antibody (AA 138-166)

Catalog No. ABIN1881991

Product Details anti-VAX2 Antibody

Target: VAX2 (Ventral Anterior Homeobox 2 (VAX2))

Binding Specificity: AA 138-166

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VAX2 antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This VAX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 138-166 amino acids from the Central region of human VAX2.

Clone: RB41016

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-VAX2 antibody (ABIN1881991)

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).

Talmud, Drenos, Shah, Shah, Palmen, Verzilli, Gaunt, Pallas, Lovering, Li, Casas, Sofat, Kumari, Rodriguez, Johnson, Newhouse, Dominiczak, Samani, Caulfield, Sever, Stanton, Shields, Padmanabhan et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, (2009) (PubMed).

Barbieri, Lupo, Bulfone, Andreazzoli, Mariani, Fougerousse, Consalez, Borsani, Beckmann, Barsacchi, Ballabio, Banfi: "A homeobox gene, vax2, controls the patterning of the eye dorsoventral axis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 19, pp. 10729-34, (1999) (PubMed).

Target Details for VAX2

Target: VAX2 (Ventral Anterior Homeobox 2 (VAX2))

Alternative Name: VAX2 (VAX2 Products)

Background: This gene encodes a homeobox protein and is almost exclusively expressed in the ventral portion of the retina during development. In mouse studies, this gene was found to be required for the correct formation of the optic fissure and other aspects of retinal development.

Molecular Weight: 30874

NCBI Accession: NP_036608

UniProt: Q9UIW0