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GLYT1 antibody (AA 209-285) (Biotin)

GLYT1 Reactivity: Rat, Human, Mouse WB, ELISA, IHC (p), IHC (fro) Host: Rabbit Polyclonal Biotin
Catalog No. ABIN1392259
  • Target See all GLYT1 Antibodies
    GLYT1 (Glycine Transporter 1 (GLYT1))
    Binding Specificity
    • 14
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 209-285
    Reactivity
    • 23
    • 22
    • 21
    • 5
    • 5
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    Rat, Human, Mouse
    Host
    • 24
    Rabbit
    Clonality
    • 24
    Polyclonal
    Conjugate
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GLYT1 antibody is conjugated to Biotin
    Application
    • 23
    • 13
    • 13
    • 5
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Cross-Reactivity
    Human, Mouse, Rat
    Predicted Reactivity
    Dog,Cow,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Glyt1/SLC6A9
    Isotype
    IgG
    Top Product
    Discover our top product GLYT1 Primary Antibody
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C for 12 months.
    Expiry Date
    12 months
  • Target
    GLYT1 (Glycine Transporter 1 (GLYT1))
    Alternative Name
    Glyt1/SLC6A9 (GLYT1 Products)
    Synonyms
    GLYT1 antibody, Glyt-1 antibody, Glyt1 antibody, GLYT-1 antibody, GLYT-1b antibody, glyt1 antibody, slc6a9 antibody, glyT-1 antibody, glyT1 antibody, solute carrier family 6 member 9 antibody, solute carrier family 6 (neurotransmitter transporter, glycine), member 9 antibody, glycine transporter 1 antibody, SLC6A9 antibody, Slc6a9 antibody, glyt1 antibody, slc6a9 antibody
    Background

    Synonyms: glycine transporter 1, Glyt 1, GlyT-1 antibodyGlyT1, SC6A9_HUMAN, SLC6A9, sodium and chloride dependent glycine transporter 1, Sodium- and chloride-dependent glycine transporter 1, Solute carrier family 6 member 9.

    Background: Na+/Cl- dependent neurotransmitter transporters are a superfamily of transmembrane proteins that contain 12 membrane spanning regions (1). Specifically, the highly hydrophobic Na+/Cl- dependent glycine transporters (GlyT) are crucial for the termination of neurotransmission at glycinergic synapses (2,3). Two different GlyT genes encode GlyT2 and GlyT1, which exists as two isoforms produced by alternative splicing of the same gene located on human chromosome 1p31.3 (3,4). The GlyT1 gene may be an early marker of neural development and encodes glia-specific transporter proteins (3). Although GlyT1 and GlyT2 are both expressed in the brain and spinal cord, each shows a unique pattern of expression (3,5,6). GlyT1 is found only in the white matter of the CNS, whereas GlyT2 is found in the gray matter of the CNS as well as in macrophages and mast cells in peripheral tissues (3,5). The anatomic distribution of GlyT2 mRNA suggests that glycine may act as a supraspinal neurotransmitter and may function as a chemical messenger outside the CNS (5).

    Gene ID
    6536
    UniProt
    P48067
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