HS6ST1 antibody (AbBy Fluor® 350)

Catalog No. ABIN1393713

The AbBy Fluor® 350-conjugated Rabbit Polyclonal anti-HS6ST1 antibody (ABIN1393713) specifically detects HS6ST1 in WB. The antibody is reactive with Human samples.

Quick Overview for HS6ST1 antibody (AbBy Fluor® 350) (ABIN1393713)

Target: HS6ST1 (Heparan Sulfate 6-O-Sulfotransferase 1 (HS6ST1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HS6ST1 antibody is conjugated to AbBy Fluor® 350

Application: Western Blotting (WB)

Product Details anti-HS6ST1 Antibody (AbBy Fluor® 350)

Purpose: HS6ST1 Polyclonal Antibody, AbBy Fluor-350 Conjugated

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HS6ST1

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for HS6ST1

Target: HS6ST1 (Heparan Sulfate 6-O-Sulfotransferase 1 (HS6ST1))

Alternative Name: Hs6st1

Background:

Synonyms: 6OST 1, 6OST1, DKFZp547H098, FLJ25392, H6 ST1, H6ST 1, H6ST1_HUMAN, Heparan sulfate 6 O sulfotransferase 1, Heparan sulfate 6 sulfotransferase, Heparan sulphate 6 O sulphotransferase 1, Heparan-sulfate 6-O-sulfotransferase 1, HS6 ST1, HS6ST 1, HS6ST , HS6ST-1, HS6ST1, MGC116899, MGC116901.

Background: Heparan sulfate structures, which are responsible for executing multiple biologic activities, are generated and regulated by heparan sulfate (HS) biosynthetic enzymes. HS6ST1 (heparan sulfate 6-O-sulfotransferase 1), also known as HS6ST, is a 411 amino acid single-pass type II membrane protein that exists as multiple alternatively spliced isoforms and belongs to the sulfotransferase 6 family. Expressed in fetal brain, HS6ST1 functions as a 6-O-sulfation enzyme that specifically catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to the N-sulfoglucosamine residue (GlcNS) HS. HS6ST1 is subject to post-translational N-glycosylation and is encoded by a functional gene on human chromosome 2 and a pseudogene on human chromosome 1 (known as LOC728969).

Pathways: Glycosaminoglycan Metabolic Process