METRN antibody (AA 101-200) (AbBy Fluor® 350)

Catalog No. ABIN1393905

The AbBy Fluor® 350-conjugated Rabbit Polyclonal anti-METRN antibody (ABIN1393905) specifically detects METRN in WB, IF (cc) and IF (p). The antibody is reactive with Mouse samples.

Quick Overview for METRN antibody (AA 101-200) (AbBy Fluor® 350) (ABIN1393905)

Target: METRN (Meteorin, Glial Cell Differentiation Regulator (METRN))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This METRN antibody is conjugated to AbBy Fluor® 350

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-METRN Antibody (AbBy Fluor® 350)

Binding Specificity: AA 101-200

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Cow

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human METRN

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for METRN

Target: METRN (Meteorin, Glial Cell Differentiation Regulator (METRN))

Alternative Name: METRN

Background:

Synonyms: C16orf23, c380A1.2, Meteorin, Meteorin precursor, meteorin, glial cell dferentiation regulator, Metrn, METRN_HUMAN, MGC2601.

Background: Meteorin is a secreted protein belonging to the Meteorin family that contains 293 amino acids and promotes axonal extension, axonal network formation and regulates glial cell differentiation. Expressed in radial glia and undifferentiated neural progenitors of the central and peripheral nervous system, Meteorin is encoded by a gene located on human chromosome 16, which encodes over 900 genes and comprises nearly 3 % of the human genome. The GAN (Gigaxonin) gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.