NRARP antibody (AA 41-114) (Biotin)

Catalog No. ABIN1394071

This Rabbit Polyclonal antibody specifically detects NRARP in WB, ELISA, IHC (fro) and IHC (p). It exhibits reactivity toward Human.

Quick Overview for NRARP antibody (AA 41-114) (Biotin) (ABIN1394071)

Target: NRARP (NOTCH-Regulated Ankyrin Repeat Protein (NRARP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NRARP antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-NRARP Antibody (Biotin)

Binding Specificity: AA 41-114

Predicted Reactivity: Human,Mouse,Rat,Cow,Sheep,Pig,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NRARP

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for NRARP

Target: NRARP (NOTCH-Regulated Ankyrin Repeat Protein (NRARP))

Alternative Name: NRARP

Background:

Synonyms: MGC61598, Notch regulated ankyrin repeat containing protein, NOTCH regulated ankyrin repeat protein, Notch-regulated ankyrin repeat-containing protein, nrarp, NRARP_HUMAN.

Background: Nrarp (NOTCH-regulated ankyrin repeat protein) is a 114 amino acid protein that contains two ANK repeats and is thought to play a role in the formation of somites. The gene encoding Nrarp maps to human chromosome 9, which contains 145 million base pairs and comprises 4 % of the human genome, encoding nearly 900 genes. Hereditary hemorrhagic telangiectasia and Familial dysautonomia are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in translocations that lead to the aberrant production of a BCR-ABL fusion protein often found in leukemias.