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RPS6KB2 antibody (Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 2) AA 281-380 (Biotin) Primary Antibody

RPS6KB2 Reactivity: Mouse, Rat IHC (fro), IHC (p), WB Host: Rabbit Polyclonal Biotin
Catalog No. ABIN1396842
$453.20
Plus shipping costs $45.00
100 μL
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  • Target See all RPS6KB2 Antibodies
    RPS6KB2
    Binding Specificity
    • 17
    • 15
    • 15
    • 15
    • 15
    • 14
    • 10
    • 9
    • 9
    • 8
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 281-380
    Reactivity
    • 113
    • 56
    • 55
    • 2
    • 2
    • 2
    • 1
    • 1
    Mouse, Rat
    Host
    • 148
    • 24
    • 1
    Rabbit
    Clonality
    • 151
    • 22
    Polyclonal
    Conjugate
    • 56
    • 16
    • 15
    • 14
    • 7
    • 7
    • 7
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    This RPS6KB2 antibody is conjugated to Biotin
    Application
    • 112
    • 85
    • 53
    • 53
    • 28
    • 27
    • 20
    • 12
    • 9
    • 5
    • 5
    • 1
    Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    Predicted Reactivity
    Human
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human p70 S6 kinase beta
    Isotype
    IgG
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C
    Expiry Date
    12 months
  • Target
    RPS6KB2
    Alternative Name
    p70 S6 kinase beta (RPS6KB2 Products)
    Synonyms
    KLS, P70-beta, P70-beta-1, P70-beta-2, S6K-beta2, S6K2, SRK, STK14B, p70(S6K)-beta, p70S6Kb, 70kDa, ribosomal protein S6 kinase B2, ribosomal protein S6 kinase, polypeptide 2, RPS6KB2, Rps6kb2
    Background

    This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. [provided by RefSeq, Jan 2013].

    Subcellular location: Cytoplasm, Nucleus

    Synonyms: 70 kDa ribosomal protein S6 kinase 1, P70 S6K, P70 S6 Kinase beta, KS6B1_HUMAN, p70 alpha, P70 beta 1, P70 beta 1, p70 ribosomal S6 kinase alpha, p70 ribosomal S6 kinase beta 1, p70 ribosomal S6 kinase beta 1, p70 S6 kinase alpha, P70 S6 Kinase, p70 S6 kinase, alpha 1, p70 S6 kinase, alpha 2, p70 S6K, p70 S6K-alpha, p70 S6KA, p70S6K alpha, p70S6K-alpha, p70-alpha, p70-S6K 1, p70-S6K, P70S6K, P70S6K1, p70S6Kb, p70S6Kb, PS6K, Ribosomal protein S6 kinase 70 kDa polypeptide 1, Ribosomal protein S6 kinase 70 kDa polypeptide 2, Ribosomal protein S6 kinase 70 kDa polypeptide 2, Ribosomal protein S6 kinase beta 1, Ribosomal protein S6 kinase beta-1, Ribosomal protein S6 kinase I, RPS6KB1, RPS6KB2, RPS6KB2, S6K, S6K-beta-1, S6K1, Serine/threonine kinase 14 alpha, Serine/threonine-protein kinase 14A, STK14A.

    Gene ID
    Pathways
    PI3K-Akt Signaling, RTK Signaling, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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