RPS6KB2 antibody (AA 281-380) (Biotin)

Catalog No. ABIN1396842

Product Details anti-RPS6KB2 Antibody (Biotin)

Target: RPS6KB2 (Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 2 (RPS6KB2))

Binding Specificity: AA 281-380

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPS6KB2 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human p70 S6 kinase beta

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for RPS6KB2

Target: RPS6KB2 (Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 2 (RPS6KB2))

Alternative Name: p70 S6 kinase beta (RPS6KB2 Products)

Background:

Synonyms: 70 kDa ribosomal protein S6 kinase 1, P70 S6K, P70 S6 Kinase beta, KS6B1_HUMAN, p70 alpha, P70 beta 1, P70 beta 1, p70 ribosomal S6 kinase alpha, p70 ribosomal S6 kinase beta 1, p70 ribosomal S6 kinase beta 1, p70 S6 kinase alpha, P70 S6 Kinase, p70 S6 kinase, alpha 1, p70 S6 kinase, alpha 2, p70 S6K, p70 S6K-alpha, p70 S6KA, p70S6K alpha, p70S6K-alpha, p70-alpha, p70-S6K 1, p70-S6K, P70S6K, P70S6K1, p70S6Kb, p70S6Kb, PS6K, Ribosomal protein S6 kinase 70 kDa polypeptide 1, Ribosomal protein S6 kinase 70 kDa polypeptide 2, Ribosomal protein S6 kinase 70 kDa polypeptide 2, Ribosomal protein S6 kinase beta 1, Ribosomal protein S6 kinase beta-1, Ribosomal protein S6 kinase I, RPS6KB1, RPS6KB2, RPS6KB2, S6K, S6K-beta-1, S6K1, Serine/threonine kinase 14 alpha, Serine/threonine-protein kinase 14A, STK14A.

Background: This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. [provided by RefSeq, Jan 2013].

Gene ID: 6199

Pathways: PI3K-Akt Signaling, RTK Signaling, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway