NFATC4 antibody (AA 480-530) (AbBy Fluor® 647)

Catalog No. ABIN1397426

The Rabbit Polyclonal anti-NFATC4 antibody is suitable to detect NFATC4 in samples from Human, Mouse and Rat. It has been validated for WB and IF (p).

Quick Overview for NFATC4 antibody (AA 480-530) (AbBy Fluor® 647) (ABIN1397426)

Target: NFATC4 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 4 (NFATC4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NFATC4 antibody is conjugated to AbBy Fluor® 647

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-NFATC4 Antibody (AbBy Fluor® 647)

Binding Specificity: AA 480-530

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NF-ATc4

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for NFATC4

Target: NFATC4 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 4 (NFATC4))

Alternative Name: NF-ATc4

Background:

Synonyms: NFAT3, NF-AT3, NF-ATC4, Nuclear factor of activated T-cells, cytoplasmic 4, NFATc4, T-cell transcription factor NFAT3

Background: Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 and IL-4. Transcriptionally repressed by estrogen receptors, this inhibition is further enhanced by estrogen. Increases the transcriptional activity of PPARG and has a direct role in adipocyte differentiation. May play an important role in myotube differentiation. May play a critical role in cardiac development and hypertrophy. May play a role in deafferentation-induced apoptosis of sensory neurons.

Gene ID: 4776

UniProt: Q14934

Pathways: RTK Signaling, WNT Signaling