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PANK1 antibody (Biotin)

PANK1 Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal Biotin
Catalog No. ABIN1398499
  • Target See all PANK1 Antibodies
    PANK1 (Pantothenate Kinase 1 (PANK1))
    Reactivity
    Human, Mouse, Rat
    Host
    • 47
    • 3
    Rabbit
    Clonality
    • 50
    Polyclonal
    Conjugate
    • 18
    • 6
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PANK1 antibody is conjugated to Biotin
    Application
    • 43
    • 24
    • 13
    • 10
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human PANK1
    Isotype
    IgG
    Top Product
    Discover our top product PANK1 Primary Antibody
  • Application Notes
    WB 1:100-1000
    IHC-P 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C for 12 months.
    Expiry Date
    12 months
  • Target
    PANK1 (Pantothenate Kinase 1 (PANK1))
    Alternative Name
    PANK1 (PANK1 Products)
    Synonyms
    PANK antibody, 4632412I06Rik antibody, 5430426F23Rik antibody, Pank antibody, Pank1a antibody, Pank1b antibody, panK1beta antibody, PANK1 antibody, im:7149302 antibody, wu:fb51a11 antibody, zgc:158746 antibody, ATCOAA antibody, ATPANK1 antibody, T13D8.31 antibody, T13D8_31 antibody, pantothenate kinase 1 antibody, DKFZp469J1021 antibody, fb79e08 antibody, zgc:63556 antibody, wu:fb79e08 antibody, pantothenate kinase 1 antibody, pantothenate kinase 1b antibody, pantothenate kinase 1a antibody, PANK1 antibody, Pank1 antibody, pank1b antibody, EHI_183060 antibody, pank1a antibody
    Background

    Synonyms: coaA, hPanK, hPanK1, PANK, PANK1, PANK1_HUMAN, PANK1a, PANK1b, PanK1beta, Pantothenate kinase 1, Pantothenate kinase, Pantothenic acid kinase 1.

    Background: The pantothenate kinase (PANK) family of proteins catalyzes the first step in coenzyme A (CoA). Pantothenate kinase 1 (PANK1) is a 598 amino acid member of the pantothenate kinase family that plays a role in the physiological regulation of the intracellular CoA concentration. Localized to the cytoplasm, PANK1 is strongly inhibited by acetyl-CoA and manyl-CoA, as well as by high concentration of non-esterified CoA (CoASH). Four known isoforms of PANK1 exist as a result of alternative splicing events. Of these isoforms, PANK1a and PANK1b have been identified as the catalytically active isoforms. Isoform PANK1a is most highly expressed in brain, heart, kidney, liver, skeletal muscle and kidney. Isoform PANK1b is detected at much lower levels in kidney, liver, brain and testis and is not detected in heart or skeletal muscle.

    Gene ID
    53354
    UniProt
    Q8TE04
    Pathways
    Ribonucleoside Biosynthetic Process
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