NLRX1 antibody (AA 111-210) (FITC)

Catalog No. ABIN1399472

The Rabbit Polyclonal anti-NLRX1 antibody has been validated for WB, IF (cc) and IF (p). It is suitable to detect NLRX1 in samples from Human.

Quick Overview for NLRX1 antibody (AA 111-210) (FITC) (ABIN1399472)

Target: NLRX1 (NLR Family Member X1 (NLRX1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NLRX1 antibody is conjugated to FITC

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-NLRX1 Antibody (FITC)

Binding Specificity: AA 111-210

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NLR family member X1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for NLRX1

Target: NLRX1 (NLR Family Member X1 (NLRX1))

Alternative Name: NLRX1

Background:

Synonyms: NOD5, NOD9, NOD26, DLNB26, CLR11.3, NLR family member X1, Caterpiller protein 11.3, Nucleotide-binding oligomerization domain protein 26, Nucleotide-binding oligomerization domain protein 5, Nucleotide-binding oligomerization domain protein 9, NLRX1

Background: Participates in antiviral signaling. Acts as a negative regulator of MAVS-mediated antiviral responses, through the inhibition of the virus-induced RLH (RIG-like helicase)-MAVS interaction (PubMed:18200010). Has no inhibitory function on NF-Kappa-B and type 1 interferon signaling pathways, but enhances NF-Kappa-B and JUN N-terminal kinase dependent signaling through the production of reactive oxygen species (PubMed:18219313).

Gene ID: 79671

UniProt: Q86UT6

Pathways: SARS-CoV-2 Protein Interactome