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CINP antibody (Biotin)

CINP Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal Biotin
Catalog No. ABIN1400707
  • Target See all CINP Antibodies
    CINP
    Reactivity
    • 23
    • 15
    • 14
    • 1
    Human, Mouse, Rat
    Host
    • 20
    • 3
    Rabbit
    Clonality
    • 22
    • 1
    Polyclonal
    Conjugate
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CINP antibody is conjugated to Biotin
    Application
    • 17
    • 13
    • 5
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CINP
    Isotype
    IgG
    Top Product
    Discover our top product CINP Primary Antibody
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C for 12 months.
    Expiry Date
    12 months
  • Target
    CINP
    Alternative Name
    CINP (CINP Products)
    Synonyms
    2810452K22RIK antibody, RGD1563395 antibody, 1810047K05Rik antibody, 2810452K22Rik antibody, cyclin dependent kinase 2 interacting protein antibody, cyclin-dependent kinase 2-interacting protein antibody, cyclin-dependent kinase 2 interacting protein antibody, CINP antibody, Cinp antibody
    Background

    Synonyms: CINP protein, CDK2-interacting protein, CINP, CINP_HUMAN, Cyclin dependent kinase 2 interacting protein, Cyclin-dependent kinase 2-interacting protein, MGC849.

    Background: Cell cycle progression is controlled in part by a family of cyclin proteins and cyclin dependent kinases (Cdks). Cdk proteins work in concert with the cyclins to phosphorylate key substrates involved in each phase of cell cycle progression. Specifically, Cdk2 interacts with Cyclins A, B1, B3, D, or E to control cell cycle progression. The Cyclin-dependent kinase 2-interacting protein (CINP) interacts with components of the replication complex and Cdk2 and Cdc7, thereby providing a functional and physical link between Cdk2 and Cdc7 during firing of the origins of replication. However, CINP is phopshorylated by Cdc7, but not by Cdk2. CINP also interacts with ATR-interacting protein and regulates ATR-dependent signaling, resistance to replication stress and G2 checkpoint integrity.

    Gene ID
    51550
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