CCDC180 antibody (Biotin)

Catalog No. ABIN1403023

This Rabbit Polyclonal antibody specifically detects CCDC180 in WB and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for CCDC180 antibody (Biotin) (ABIN1403023)

Target: CCDC180 (Coiled-Coil Domain Containing 180 (CCDC180))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCDC180 antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CCDC180 Antibody (Biotin)

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C9orf174

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for CCDC180

Target: CCDC180 (Coiled-Coil Domain Containing 180 (CCDC180))

Alternative Name: C9orf174

Background:

Synonyms: BDAG1, Behcet's Disease Associated Gene 1, C9orf174, DKFZp434I2420, DKFZp686B2031, DKFZp686G1725, FLJ41397, FLJ50036, Hypothetical protein LOC100499483, KIAA1529, Uncharacterized protein C9orf174, CI174_HUMAN.

Background: Chromosome 9 consists of about 145 million bases and 4 % of the human genome and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias. The KIAA1529 gene product has been provisionally designated KIAA1529 pending further characterization.