SERPINI2 antibody (AbBy Fluor® 488)

Catalog No. ABIN1403164

This Rabbit Polyclonal antibody specifically detects SERPINI2 in WB and IF (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for SERPINI2 antibody (AbBy Fluor® 488) (ABIN1403164)

Target: SERPINI2 (serpin Peptidase Inhibitor, Clade I (Pancpin), Member 2 (SERPINI2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SERPINI2 antibody is conjugated to AbBy Fluor® 488

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-SERPINI2 Antibody (AbBy Fluor® 488)

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SERPINI2/PI14

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for SERPINI2

Target: SERPINI2 (serpin Peptidase Inhibitor, Clade I (Pancpin), Member 2 (SERPINI2))

Alternative Name: PI14

Background:

Synonyms: MEPI, Myoepithelium derived serine protease inhibitor, Pancpin, Pancreas specic protein TSA2004, Peptidase inhibitor 14, PI 14, PI14, Protease inhibitor 14, Serine or cysteine proteinase inhibitor clade I neuroserpin member 2, Serine or cysteine proteinase inhibitor clade I pancpin member 2, Serpin I2, Serpin peptidase inhibitor clade I pancpin member 2, TSA2004, SPI2_HUMAN, SERPINI2.

Background: SERPINI2 is a member of the serine protease inhibitor (serpin) superfamily made up of proteins which play central roles in the regulation of a wide variety of physiological processes, including coagulation, fibrinolysis, development, malignancy and inflammation. It may have a role in a growth-control, possibly growth-suppressing pathway and, when impaired, may be involved in pancreatic carcinogenesis. The protein is a member of the plasminogen activator inhibitor-1 family, a subset of the serpin superfamily whose members act as tissue-specific tPA inhibitors. Two alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene.

Gene ID: 5276