AKD1 antibody (Biotin)

Catalog No. ABIN1403269

This Rabbit Polyclonal antibody specifically detects AKD1 in WB and IHC (p). It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for AKD1 antibody (Biotin) (ABIN1403269)

Target: AKD1 (ADK1) (Adenylate Kinase Domain Containing 1 (ADK1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AKD1 antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-AKD1 Antibody (Biotin)

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human AKD1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for AKD1

Target: AKD1 (ADK1) (Adenylate Kinase Domain Containing 1 (ADK1))

Alternative Name: AKD1

Background:

Synonyms: adenylate kinase domain containing 1, adenylate kinase domain containing 2, Adenylate kinase domain-containing protein 1, Adenylate kinase domain-containing protein 2, AKD1, AKD1_HUMAN, AKD2 , C6orf224, chromosome 6 open reading frame 199, chromosome 6 open reading frame 224 Gm234, Gm7127, RP1-70A9.

Background: AKD1 is a 1,911 amino acid coiled-coil protein belonging to the adenylate kinase family. AKD1 exists as six alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 6q21. Chromosome 6 makes up nearly 6 % of the human genome and contains 170 million base pairs, which encode 1,200 genes. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. A bipolar disorder susceptibility locus is also linked to the q arm of chromosome 6. The PARK2 gene, which is associated with Parkinson's disease, and the genes encoding the major histocompatiblity complex proteins are located on chromosome 6. Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6.