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ANKRD50 antibody (Biotin)

ANKRD50 Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal Biotin
Catalog No. ABIN1404457
  • Target See all ANKRD50 products
    ANKRD50 (Ankyrin Repeat Domain 50 (ANKRD50))
    Reactivity
    • 23
    • 20
    • 16
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 23
    Rabbit
    Clonality
    • 22
    Polyclonal
    Conjugate
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ANKRD50 antibody is conjugated to Biotin
    Application
    • 23
    • 13
    • 5
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human ANKRD50
    Isotype
    IgG
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C for 12 months.
    Expiry Date
    12 months
  • Target
    ANKRD50 (Ankyrin Repeat Domain 50 (ANKRD50))
    Alternative Name
    ANKRD50 (ANKRD50 Products)
    Synonyms
    RGD1311665 antibody, AI662170 antibody, E430012K20Rik antibody, mKIAA1223 antibody, mKIAA3019 antibody, ankyrin repeat domain 50 antibody, ANKRD50 antibody, Ankrd50 antibody
    Background

    Synonyms: ANKRD50, Ankyrin repeat domain 50, Ankyrin repeat domain-containing protein 50, ANR50_HUMAN, KIAA1223.

    Background: Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes lead to severe genetic diseases, such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKRD50 (ankyrin repeat domain 50) is a 1,429 amino acid phosphoprotein that contains nineteen ANK repeats. Conserved in chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, fruit fly and mosquito, ANKRD50 is encoded by a gene that maps to human chromosome 4q28.1. Chromosome 4 represents approximately 6 % of the human genome and contains nearly 900 genes. Notably, the Huntingtin gene, which encodes an expanded glutamine tract in cases of Huntington's disease, is located on chromosome 4. FGFR-3 is also encoded by a gene that maps to human chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer. Chromosome 4 is also linked to Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.

    Gene ID
    57182
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