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COA6 antibody (Biotin)

COA6 Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal Biotin
Catalog No. ABIN1404655
  • Target See all COA6 products
    COA6 (Cytochrome C Oxidase Assembly Factor 6 Homolog (COA6))
    Reactivity
    • 23
    • 15
    • 14
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 22
    • 1
    Rabbit
    Clonality
    • 22
    • 1
    Polyclonal
    Conjugate
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This COA6 antibody is conjugated to Biotin
    Application
    • 18
    • 13
    • 6
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human C1orf31
    Isotype
    IgG
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C for 12 months.
    Expiry Date
    12 months
  • Target
    COA6 (Cytochrome C Oxidase Assembly Factor 6 Homolog (COA6))
    Alternative Name
    C1orf31 (COA6 Products)
    Synonyms
    C1orf31 antibody, cytochrome c oxidase assembly factor 6 antibody, COA6 antibody
    Background

    Synonyms: C1orf31, CA031_HUMAN, Chromosome 1 open reading frame 31, Hypothetical protein LOC388753, RP5-827C21.3, Uncharacterized protein C1orf31.

    Background: The cytochrome c oxidase (COX) family of proteins function as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimately resulting in the production of water. C1orf31 is a 125 amino acid mitochondrial protein that belongs to the cytochrome c oxidase subunit 6B family. There are three isoforms of C1orf31 that are produced as a result of alternative splicing events. The gene encoding C1orf31 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration.

    Gene ID
    388753
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