MMADHC antibody (Biotin)

Catalog No. ABIN1404787

This Rabbit Polyclonal antibody specifically detects MMADHC in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for MMADHC antibody (Biotin) (ABIN1404787)

Target: MMADHC (Methylmalonic Aciduria (Cobalamin Deficiency) CblD Type, with Homocystinuria (MMADHC))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MMADHC antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-MMADHC Antibody (Biotin)

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C2ORF25

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for MMADHC

Target: MMADHC (Methylmalonic Aciduria (Cobalamin Deficiency) CblD Type, with Homocystinuria (MMADHC))

Alternative Name: C2ORF25

Background:

Synonyms: cblD, Chromosome 2 open reading frame 25, Protein C2orf25, mitochondrial, CL25022, Methylmalonic aciduria cobalamin deficiency cblD type, with homocystinuria, Protein C2orf25, mitochondrial, MMAD_HUMAN.

Background: C2ORF25 is a mitochondrial protein and its function is not fully identified. But, Vitamin B12 (cobalamin) is an essential cofactor in several metabolic pathways. Intracellular conversion of cobalamin to adenosylcobalamin in mitochondria and to methylcobalamin in cytoplasm is necessary for homeostasis of methylmalonic acid and homocysteine. C2ORF25 encodes a protein involved in an early step of cobalamin metabolism.

Gene ID: 27249