MMADHC antibody (AA 26-142) (HRP)

Catalog No. ABIN7159660

Product Details anti-MMADHC Antibody (HRP)

Target: MMADHC (Methylmalonic Aciduria (Cobalamin Deficiency) CblD Type, with Homocystinuria (MMADHC))

Binding Specificity: AA 26-142

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MMADHC antibody is conjugated to HRP

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Methylmalonic aciduria and homocystinuria type D protein, mitochondrial protein (26-142AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MMADHC

Target: MMADHC (Methylmalonic Aciduria (Cobalamin Deficiency) CblD Type, with Homocystinuria (MMADHC))

Alternative Name: MMADHC (MMADHC Products)

Synonyms: C2orf25 antibody, CL25022 antibody, cblD antibody, 2010311D03Rik antibody, AI314967 antibody, RGD1303272 antibody, methylmalonic aciduria and homocystinuria, cblD type antibody, methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria antibody, MMADHC antibody, Mmadhc antibody

Background:

Background: Involved in cobalamin metabolism (PubMed:18385497, PubMed:23415655, PubMed:24722857, PubMed:26364851). Plays a role in regulating the biosynthesis of two coenzymes, methylcobalamin and adenosylcobalamin (PubMed:18385497, PubMed:24722857). Plays a role in regulating the proportion of methylcobalamin and adenosylcobalamin (PubMed:23415655, PubMed:24722857). Promotes oxidation of cob(II)alamin bound to MMACHC (PubMed:26364851).

Aliases: C2orf25 antibody, cblD antibody, Chromosome 2 open reading frame 25 antibody, CL25022 antibody, Methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria antibody, Methylmalonic aciduria and homocystinuria type D protein antibody, methylmalonic aciduria and homocystinuria type D protein, mitochondrial antibody, mitochondrial antibody, MMAD_HUMAN antibody, Mmadhc antibody, Protein C2orf25, mitochondrial antibody

UniProt: Q9H3L0