LCA5L antibody (Biotin)

Catalog No. ABIN1405705

This Rabbit Polyclonal antibody specifically detects LCA5L in WB and IHC (p). It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for LCA5L antibody (Biotin) (ABIN1405705)

Target: LCA5L (Leber Congenital Amaurosis 5-Like (LCA5L))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LCA5L antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-LCA5L Antibody (Biotin)

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LCA5L

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for LCA5L

Target: LCA5L (Leber Congenital Amaurosis 5-Like (LCA5L))

Alternative Name: LCA5L

Background:

Synonyms: C21ORF13, Chromosome 21 open reading frame 13, Lca5l, LCA5L_HUMAN, Leber congenital amaurosis 5 like, Leber congenital amaurosis 5 like protein, Leber congenital amaurosis 5-like protein, Lebercilin-like protein.

Background: Leber congenital amaurosis (LCA) is one of the most common causes of hereditary blindness or severe visual impairment in infants. Mutations in several genes with diverse functions mapping to two loci have been implicated in LCA causation. These proteins are involved in processes such as photoreceptor development and maintenance, phototransduction, vitamin A metabolism and protein trafficking. LCA5, also known as Lebercilin, is a ciliary protein that is widely expressed during development and localizes to the connecting cilia of photoreceptors and to the microtubules, centrioles and primary cilia of cultured mammalian cells. The Leber congenital amaurosis 5-like protein (LCA5L) is a 670 amino acid protein that belongs to the LCA5 family.

Gene ID: 150082

UniProt: O95447