NIPAL2 antibody (AA 1-100) (HRP)

Catalog No. ABIN1407140

Product Details anti-NIPAL2 Antibody (HRP)

Target: NIPAL2 (NIPA-Like Domain Containing 2 (NIPAL2))

Binding Specificity: AA 1-100

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NIPAL2 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NIPAL2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for NIPAL2

Target: NIPAL2 (NIPA-Like Domain Containing 2 (NIPAL2))

Alternative Name: NIPAL2 (NIPAL2 Products)

Synonyms: NPAL2 antibody, 9330161F08Rik antibody, Npal2 antibody, RGD1564315 antibody, NIPA like domain containing 2 antibody, NIPA-like domain containing 2 antibody, NIPAL2 antibody, Nipal2 antibody

Background:

Synonyms: NIPA like domain containing 2, NIPAL2, NPAL2, NPAL2_HUMAN.

Background: Non-imprinted in Prader-Willi/Angelman syndrome (NIPA) proteins are highly conserved receptors or transporters. A family known as the NIPA-like domain containing (NPAL) proteins are closely related to the NIPA proteins, but most are uncharacterized and their functions are unknown. NPAL2 (NIPA-like domain containing 2), also known as NIPAL2, is a 368 amino acid multi-pass membrane protein belonging to the NIPA family and is encoded by a gene located on human chromosome 8. Human chromosome 8 consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that map to chromosome 8.