TCF12 antibody (AA 51-150) (Cy7)

Catalog No. ABIN1407978

This anti-TCF12 antibody is a Rabbit Polyclonal antibody detecting TCF12 in WB, IF (cc) and IF (p). Suitable for Human and Rat.

Quick Overview for TCF12 antibody (AA 51-150) (Cy7) (ABIN1407978)

Target: TCF12 (Transcription Factor 12 (TCF12))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TCF12 antibody is conjugated to Cy7

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-TCF12 Antibody (Cy7)

Binding Specificity: AA 51-150

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Sheep,Horse,Rabbit,Zebrafish

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TCF12

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for TCF12

Target: TCF12 (Transcription Factor 12 (TCF12))

Alternative Name: TCF12/HEB

Background:

Synonyms: bHLHb20, Class B basic helix-loop-helix protein 20, DNA binding protein HTF4, DNA-binding protein HTF4, E box binding protein, E-box-binding protein, HEB, HTF4, HTF4_HUMAN, TCF-12, Tcf12, Transcription factor 12, Transcription factor HTF-4, Transcription factor HTF4.

Background: Differentiation of myogenic cells is regulated by multiple positively and negatively acting factors. One well characterized family of helix-loop-helix (HLH) proteins known to play an important role in the regulation of muscle cell development includes Myo D, myogenin, Myf-5 and Myf-6 (also designated MRF-4 or herculin). Myo D transcription factors form heterodimers with products of a more widely expressed family of bHLH genes, the E family, which consists of at least three distinct genes: E2A, IF2 and HEB. Myo D-E heterodimers bind avidly to consensus (CANNTG) E box target sites that are functionally important elements in the upstream regulatory sequences of many muscle-specific terminal differentiation genes. Both homo- and hetero-oligomers of these proteins are able to distinguish very closely related E box proteins and are believed to play important roles in lineage specific gene expression.

Gene ID: 6938

UniProt: Q99081

Pathways: SARS-CoV-2 Protein Interactome