EPH Receptor B3 antibody (AA 121-220) (Cy7)

Catalog No. ABIN1408230

This anti-EPH Receptor B3 antibody is a Rabbit Polyclonal antibody detecting EPH Receptor B3 in WB, IF (cc) and IF (p). Suitable for Human.

Quick Overview for EPH Receptor B3 antibody (AA 121-220) (Cy7) (ABIN1408230)

Target: EPH Receptor B3 (EPHB3)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EPH Receptor B3 antibody is conjugated to Cy7

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-EPH Receptor B3 Antibody (Cy7)

Binding Specificity: AA 121-220

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human EPHB3/Eph receptor B3

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for EPH Receptor B3

Target: EPH Receptor B3 (EPHB3)

Alternative Name: EPHB3/Eph receptor B3

Background:

Synonyms: Cek10, EK2, Embryonic kinase 2, EPH Like Tyrosine Kinase 2, EPH-like kinase 2, ephb3, EPHB3_HUMAN, Ephrin receptor EphB3, Ephrin type B receptor 3, Ephrin type-B receptor 3, ETK2, hEK2, Human Embryo Kinase 2, Mdk5, Sek4, TYRO6, Tyrosine protein kinase receptor HEK2, Tyrosine protein kinase TYRO6, Tyrosine-protein kinase TYRO6.

Background: The Eph subfamily represents the largest group of receptor protein tyrosine kinases identified to date (13). While the biological activities of these receptors have yet to be determined, there is increasing evidence that they are involved in central nervous system function and in development (13). The Eph subfamily receptors of human origin (and their murine/avian homologs) include EphA1 (Eph), EphA2 (Eck), EphA3 (Hek4), EphA4 (Hek8), EphA5 (Hek7), EphA6 (Hek12), EphA7 (Hek11/MDK1), EphA8 (Hek3), EphB1 (Hek6), EphB2 (Hek5), EphB3 (Cek10, Hek2), EphB4 (Htk), EphB5 (Hek9) and EphB6 (Mep). Ligands for Eph receptors include ephrin-A4 (LERK-4) which binds EphA3 and EphB1. In addition, ephrin-A2 (ELF-1) has been described as the ligand for EphA4, ephrin-A3 (Ehk1-L) as the ligand for EphA5 and ephrin-B2 (Htk-L) as the ligand for EphB4 (Htk) (47).

Pathways: RTK Signaling