ERC2 antibody (AA 361-460) (HRP)

Catalog No. ABIN1408616

The Rabbit Polyclonal anti-ERC2 antibody is suitable to detect ERC2 in samples from Human. It has been validated for WB, ELISA, IHC (fro) and IHC (p).

Quick Overview for ERC2 antibody (AA 361-460) (HRP) (ABIN1408616)

Target: ERC2 (ELKS/RAB6-Interacting/CAST Family Member 2 (ERC2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERC2 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ERC2 Antibody (HRP)

Binding Specificity: AA 361-460

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CAST1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ERC2

Target: ERC2 (ELKS/RAB6-Interacting/CAST Family Member 2 (ERC2))

Alternative Name: ERC2/CAST1

Background:

Synonyms: Cast, CAST1, CAZ-associated structural protein 1, Cmbp gene name, Cytomatrix protein p110, ERC protein 2, KIAA0378, ERC2_HUMAN.

Background: ERCs (ERC1 and ERC2) also referred to as ELKS and CAST are related proteins which share an identical C-terminal sequence. They interact with the conserved RIM PDZ domain via an unusual PDZ binding motif. ERC2/CAST 1 is only expressed as a single RIM binding variant. All ERCs have been shown to interact with Rab6, a protein involved in membrane trafficking at the Golgi complex. The function of these proteins has not been determined yet. They may link Rab6 mediated non-neuronal membrane traffic at the Golgi complex to neuronal membrane traffic at the active zone executed via RIMs.