Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

RCAN3 antibody (AA 151-241) (HRP)

RCAN3 Reactivity: Mouse, Rat WB, ELISA, IHC (p), IHC (fro) Host: Rabbit Polyclonal HRP
Catalog No. ABIN1409780
  • Target See all RCAN3 Antibodies
    RCAN3 (RCAN Family Member 3 (RCAN3))
    Binding Specificity
    • 15
    • 14
    • 9
    • 8
    • 7
    • 6
    • 1
    AA 151-241
    Reactivity
    • 46
    • 31
    • 15
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Mouse, Rat
    Host
    • 59
    • 1
    Rabbit
    Clonality
    • 59
    • 1
    Polyclonal
    Conjugate
    • 15
    • 7
    • 6
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This RCAN3 antibody is conjugated to HRP
    Application
    • 46
    • 34
    • 21
    • 13
    • 13
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Cross-Reactivity
    Mouse, Rat
    Predicted Reactivity
    Human,Dog,Cow,Sheep,Pig,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Calcipressin 3
    Isotype
    IgG
    Top Product
    Discover our top product RCAN3 Primary Antibody
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Handling Advice
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    RCAN3 (RCAN Family Member 3 (RCAN3))
    Alternative Name
    Calcipressin 3 (RCAN3 Products)
    Synonyms
    DSCR1L2 antibody, rcn3 antibody, hrcn3 antibody, mcip3 antibody, dscr1l2 antibody, MGC145788 antibody, MCIP3 antibody, RCN3 antibody, hRCN3 antibody, Dscr1l2 antibody, AU041093 antibody, Csp3 antibody, wu:fc68f05 antibody, zgc:113155 antibody, zgc:91820 antibody, RCAN family member 3 antibody, calcipressin-3 antibody, regulator of calcineurin 3 antibody, RCAN3 antibody, Tsp_08182 antibody, rcan3 antibody, Rcan3 antibody
    Background

    Synonyms: Calcipressin-3, Down syndrome candidate region 1 like 2, regulator of calcineurin 3, Down syndrome candidate region 1 like protein 2, Down syndrome candidate region 1-like protein 2, Down syndrome critical region gene 1 like 2, DSCR1L2, hRCN3, MCIP3, Myocyte enriched calcineurin interacting protein 3, Myocyte-enriched calcineurin-interacting protein 3, RCAN family member 3, RCAN3, RCAN3_HUMAN, RCN3, Regulator of calcineurin 3.

    Background: Calcineurin is a Ca(2+) dependent protein phosphatase that is involed in several neuornal functions. Proteins belonging to the RCAN (Regulator of calcineurin) family modulate the activity of Calcineurin through a valine-rich region within their carboxyl tail. RCANs compete with NFATs (Nuclear factor of activated T-cells) for binding to the same docking site in calcineurin, which results in either inhibition or activation of calcineurin activity. Calcipressin-2, also known as RCAN2 and DSCR1L1 (Down syndrome candidate region 1-like 1), is a 197 amino acid protein that is highly expressed in both the cytoplasm and nucleus of neurons and is the only RCAN family member that is found in glial cells. Calcipressin-3, also known as RCAN3 and DSCR1L2 (Down syndrome candidate region 1-like protein 2), is a 241 amino acid protein that potentially is involved in central nervous system development. Calcipressin-3 interacts with cardiac troponin I, suggesting that it may play a role in cardiac contraction events.

You are here:
Support