Kcne3 antibody (AA 51-103) (Cy5.5)

Catalog No. ABIN1410485

The Rabbit Polyclonal anti-Kcne3 antibody is suitable to detect Kcne3 in samples from Human. It has been validated for WB, IF (cc) and IF (p).

Quick Overview for Kcne3 antibody (AA 51-103) (Cy5.5) (ABIN1410485)

Target: Kcne3 (Potassium Voltage-Gated Channel, Isk-Related Family, Member 3 (Kcne3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Kcne3 antibody is conjugated to Cy5.5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-Kcne3 Antibody (Cy5.5)

Binding Specificity: AA 51-103

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human KCNE3

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Kcne3

Target: Kcne3 (Potassium Voltage-Gated Channel, Isk-Related Family, Member 3 (Kcne3))

Alternative Name: KCNE3

Background:

Synonyms: HYPP, HOKPP, MiRP2, Potassium voltage-gated channel subfamily E member 3, MinK-related peptide 2, Minimum potassium ion channel-related peptide 2, Potassium channel subunit beta MiRP2, KCNE3

Background: Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 (PubMed:12954870). Associated with KCNC4/Kv3.4 is proposed to form the subthreshold voltage-gated potassium channel in skeletal muscle and to establish the resting membrane potential (RMP) in muscle cells. Associated with KCNQ1/KCLQT1 may form the intestinal cAMP-stimulated potassium channel involved in chloride secretion that produces a current with nearly instantaneous activation with a linear current-voltage relationship.

Gene ID: 10008

UniProt: Q9Y6H6