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NERP-1 antibody (AA 231-330) (Cy3)

NERP-1 Reactivity: Mouse, Rat, Zebrafish (Danio rerio) WB, IF (cc), IF (p) Host: Rabbit Polyclonal Cy3
Catalog No. ABIN1411257
  • Target See all NERP-1 Antibodies
    NERP-1 (Neuroendocrine Regulatory Peptide 1 (NERP-1))
    Binding Specificity
    • 14
    • 4
    AA 231-330
    Reactivity
    • 15
    • 14
    • 14
    • 4
    Mouse, Rat, Zebrafish (Danio rerio)
    Host
    • 18
    Rabbit
    Clonality
    • 18
    Polyclonal
    Conjugate
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NERP-1 antibody is conjugated to Cy3
    Application
    • 14
    • 12
    • 12
    • 7
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Mouse, Rat, Zebrafish (Danio rerio)
    Predicted Reactivity
    Human,Cow,Guinea Pig
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human NERP1
    Isotype
    IgG
    Top Product
    Discover our top product NERP-1 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    NERP-1 (Neuroendocrine Regulatory Peptide 1 (NERP-1))
    Alternative Name
    VGF/NERP-1 (NERP-1 Products)
    Synonyms
    Gm1052 antibody, VGF nerve growth factor inducible antibody, VGF antibody, Vgf antibody
    Background

    Synonyms: Nerve growth factor inducible, Neurosecretory protein VGF, VGF, VGF_HUMAN, SCG7, SgVII, Neuroendocrine regulatory peptide-1, NERP-1, NERP1

    Background: This gene is specifically expressed in a subpopulation of neuroendocrine cells, and is upregulated by nerve growth factor. The structural organization of this gene is similar to that of the rat gene, and both the translated and the untranslated regions show a high degree of sequence similarity to the rat gene. The encoded secretory protein also shares similarities with the secretogranin/chromogranin family, however, its exact function is not known. Nerve growth factor (NGF) is a peptide that plays a key role in the differentiation and survival of neurons in the peripheral nervous system (PNS) and the central nervous system (CNS). VGF is a peptide synthesized and secreted by neurons and is upregulated by NGF in the PC12 cell line. VGF is widely expressed in both the PNS and CNS, but is especially abundant in the adult hypothalamus. VGF plays an essential role in how the brain regulates energy expenditure and body weight. Its expression is rapidly induced by injury, the circadian clock, and neuronal activity.

    Gene ID
    7425
    UniProt
    O15240
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