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LIN7C antibody (AA 86-197) (HRP)

The Rabbit Polyclonal anti-LIN7C antibody has been validated for WB, ELISA, IHC (p) and IHC (fro). It is suitable to detect LIN7C in samples from Human.
Catalog No. ABIN1411718

Quick Overview for LIN7C antibody (AA 86-197) (HRP) (ABIN1411718)

Target

See all LIN7C Antibodies
LIN7C (Lin-7 Homolog C (LIN7C))

Reactivity

  • 31
  • 6
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
Human

Host

  • 31
Rabbit

Clonality

  • 31
Polyclonal

Conjugate

  • 13
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This LIN7C antibody is conjugated to HRP

Application

  • 31
  • 13
  • 13
  • 13
  • 11
  • 7
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Binding Specificity

    • 14
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 86-197

    Predicted Reactivity

    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Zebrafish

    Purification

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human LIN7C

    Isotype

    IgG
  • Application Notes

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Handling Advice

    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Expiry Date

    12 months
  • Target

    LIN7C (Lin-7 Homolog C (LIN7C))

    Alternative Name

    LIN7C

    Background

    Synonyms: LIN 7 C, Lin 7 homolog C C. elegans, LIN 7 protein 3, LIN 7C, LIN7 protein 3, MALS 3, MALS3, Mammalian lin seven protein 3, Veli 3 protein, VELI3, Vertebrate lin 7 homolog 3, LIN7C_HUMAN.

    Background: Velis are a family of small synaptic proteins that interact with other proteins at the post-synaptic density (PSD) of neuronal synapses. Velis contain the PDZ motif involved in recruiting cell adhesion molecules, receptors, and channels. Veli1 (also designated Lin-7A and MALS-1), Veli2 (also designated Lin-7B and MALS-2), and Veli3 (also designated Lin-7C and MALS-3) are mammalian homologs of C. elegans LIN-7. Veli proteins are ubiquitously expressed with high expression in brain, liver, and testis. Velis are localized at the synaptic junctions in neurons. Velis bind to CASK, a neurexin-binding protein highly concentrated in synapses, and Mint1, a binding partner with a vesicle trafficking protein.

    Pathways

    Synaptic Membrane
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