LIN7C antibody (AA 86-197) (HRP)
Quick Overview for LIN7C antibody (AA 86-197) (HRP) (ABIN1411718)
Target
See all LIN7C AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 86-197
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Predicted Reactivity
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Zebrafish
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Purification
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human LIN7C
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Isotype
- IgG
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Application Notes
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Handling Advice
- Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Expiry Date
- 12 months
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- LIN7C (Lin-7 Homolog C (LIN7C))
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Alternative Name
- LIN7C
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Background
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Synonyms: LIN 7 C, Lin 7 homolog C C. elegans, LIN 7 protein 3, LIN 7C, LIN7 protein 3, MALS 3, MALS3, Mammalian lin seven protein 3, Veli 3 protein, VELI3, Vertebrate lin 7 homolog 3, LIN7C_HUMAN.
Background: Velis are a family of small synaptic proteins that interact with other proteins at the post-synaptic density (PSD) of neuronal synapses. Velis contain the PDZ motif involved in recruiting cell adhesion molecules, receptors, and channels. Veli1 (also designated Lin-7A and MALS-1), Veli2 (also designated Lin-7B and MALS-2), and Veli3 (also designated Lin-7C and MALS-3) are mammalian homologs of C. elegans LIN-7. Veli proteins are ubiquitously expressed with high expression in brain, liver, and testis. Velis are localized at the synaptic junctions in neurons. Velis bind to CASK, a neurexin-binding protein highly concentrated in synapses, and Mint1, a binding partner with a vesicle trafficking protein.
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Pathways
- Synaptic Membrane
Target
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