NAV2 antibody (AA 21-120) (HRP)

Catalog No. ABIN1411838

The Rabbit Polyclonal anti-NAV2 antibody has been validated for WB and ELISA. It is suitable to detect NAV2 in samples from Human.

Quick Overview for NAV2 antibody (AA 21-120) (HRP) (ABIN1411838)

Target: NAV2 (Neuron Navigator 2 (NAV2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NAV2 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA

Product Details anti-NAV2 Antibody (HRP)

Binding Specificity: AA 21-120

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Dog,Cow,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NAV2/RAINB1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for NAV2

Target: NAV2 (Neuron Navigator 2 (NAV2))

Alternative Name: NAV2/RAINB1

Background:

Synonyms: HELAD1, Helicase, APC down regulated 1, KIAA1419, mCG 145366, mKIAA3015, NAV 2, Neuron navigator 2, POMFIL2, Pore membrane and/or filament interacting like protein 2, RAINB1, RAINB2, Retinoic acid inducible in neuroblastoma 1, Steerin 2, STEERIN2, Unc 53 homolog 2, Unc53H2, NAV2_HUMAN.

Background: Neuron navigator 2 (NAV2), also known as RAINB1 (retinoic acid inducible in neuroblastoma 1), POMFIL2 (pore membrane and/or filament-interacting-like protein 2), HELAD1 (helicase APC down-regulated 1), unc53H2 or steerin-2, is a 2,488 amino acid nuclear protein that plays a role in the development of sensory organs. Existing as thirteen alternatively spliced isoforms, Neuron navigator 2 displays 3' to 5' helicase activity and exonuclease activity and participates in the catalysis of ATP to ADP. Neuron navigator 2 is highly expressed in the nervous system of developing embryos and colon carcinomas, as well as in liver, brain and kidney. Lower levels of expression are found in lung, thyroid, spinal cord, heart, placenta and mammary gland. Neuron navigator 2 belongs to the Nav/unc-53 family and contains one CH (calponin-homology) domain.

Gene ID: 89797

UniProt: Q8IVL1

Pathways: Sensory Perception of Sound