GABRG3 antibody (Cy5)

Catalog No. ABIN1412932

This Rabbit Polyclonal antibody specifically detects GABRG3 in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for GABRG3 antibody (Cy5) (ABIN1412932)

Target: GABRG3 (gamma-aminobutyric Acid (GABA) A Receptor, gamma 3 (GABRG3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GABRG3 antibody is conjugated to Cy5

Application: Western Blotting (WB)

Product Details anti-GABRG3 Antibody (Cy5)

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GABRG3/GABA A Receptor gamma 3

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for GABRG3

Target: GABRG3 (gamma-aminobutyric Acid (GABA) A Receptor, gamma 3 (GABRG3))

Alternative Name: Gabrg3/Gaba A Receptor gamma 3

Background:

Synonyms: GABAA receptor, GABAA receptor subunit gamma 3, GABR G3, GABRG 3, GABRG3, Gamma aminobutyric acid GABA A receptor gamma 3, Gamma aminobutyric acid A receptor gamma 3, Gamma aminobutyric acid receptor subunit gamma 3, GBRG3_HUMAN.

Background: GAD-65 and GAD-67, glutamate decarboxylases, function to catalyze the production of GABA (gamma-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl- conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct. Members of the GABAA receptor family include GABAA R Alpha 1-6, GABAA R Beta 1-3, GABAA R Gamma 1-3, GABAA R Delta, GABAA R Epsilon, GABAA R Zeta 1 and GABAA R Zeta 2. The GABAB family is composed of GABAB R1 Alpha and GABAB R1 Beta. GABA transporters have also been identified and include GABA T-1, GABA T-2 and GABA T-3 (also designated GAT-1, -2, and -3). The GABA transporters function to terminate GABA action.