ACCN4 antibody (AA 451-550) (Cy7)

Catalog No. ABIN1413222

This anti-ACCN4 antibody is a Rabbit Polyclonal antibody detecting ACCN4 in IF (cc) and IF (p). Suitable for Human.

Quick Overview for ACCN4 antibody (AA 451-550) (Cy7) (ABIN1413222)

Target: ACCN4 (Amiloride-Sensitive Cation Channel 4, Pituitary (ACCN4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACCN4 antibody is conjugated to Cy7

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-ACCN4 Antibody (Cy7)

Binding Specificity: AA 451-550

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ACCN4/ASIC4

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ACCN4

Target: ACCN4 (Amiloride-Sensitive Cation Channel 4, Pituitary (ACCN4))

Alternative Name: ACCN4

Background:

Synonyms: Accn4, ACCN4_HUMAN, Acid sensing proton gated ion channel family member 4, Acid sensing ion channel 4, Acid-sensing ion channel 4, Amiloride sensitive cation channel 4, Amiloride sensitive cation channel 4 pituitary, Amiloride sensitive cation channel family member 4 pituitary, Amiloride-sensitive cation channel 4, Amiloride-sensitive cation channel 4, ASIC4, BNAC4, Brain sodium channel 4, pituitary.

Background: This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC. [provided by RefSeq, Feb 2012].