Neurotrophin 3 antibody (AA 101-220) (HRP)

Catalog No. ABIN1414287

This anti-Neurotrophin 3 antibody is a Rabbit Polyclonal antibody detecting Neurotrophin 3 in WB and ELISA. Suitable for Mouse and Rat.

Quick Overview for Neurotrophin 3 antibody (AA 101-220) (HRP) (ABIN1414287)

Target: Neurotrophin 3 (NTF3)

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Neurotrophin 3 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA

Product Details anti-Neurotrophin 3 Antibody (HRP)

Binding Specificity: AA 101-220

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Cow,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NT-3

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Neurotrophin 3

Target: Neurotrophin 3 (NTF3)

Alternative Name: Neurotrophin 3

Background:

Synonyms: HDNF, MGC129711, Nerve growth factor 2, Neurotrophic factor, Neurotrophin 3 precursor, Neurotrophin-3, Neurotrophin3, NGF 2, NGF-2, NGF2, NT 3, NT-3, NT3, NTF 3, NTF3, NTF3_HUMAN.

Background: The protein encoded by this gene is a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse. [provided by RefSeq, Jul 2008].

Gene ID: 4908

UniProt: P20783

Pathways: RTK Signaling, Neurotrophin Signaling Pathway