Prolactin Receptor antibody (AA 251-350) (HRP)

Catalog No. ABIN1415217

This anti-Prolactin Receptor antibody is a Rabbit Polyclonal antibody detecting Prolactin Receptor in WB, ELISA, IHC (p) and IHC (fro). Suitable for Human, Rat and Mouse.

Quick Overview for Prolactin Receptor antibody (AA 251-350) (HRP) (ABIN1415217)

Target: Prolactin Receptor (PRLR)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Prolactin Receptor antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Prolactin Receptor Antibody (HRP)

Binding Specificity: AA 251-350

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Prolactin Receptor

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Prolactin Receptor

Target: Prolactin Receptor (PRLR)

Alternative Name: PRLR

Background:

Synonyms: HPRL, MFAB, hPRLrI, Prolactin receptor, PRL-R, PRLR

Background: This is a receptor for the anterior pituitary hormone prolactin (PRL). Acts as a prosurvival factor for spermatozoa by inhibiting sperm capacitation through suppression of SRC kinase activation and stimulation of AKT. Isoform 4 is unable to transduce prolactin signaling. Isoform 6 is unable to transduce prolactin signaling.

Gene ID: 5618

UniProt: P16471

Pathways: JAK-STAT Signaling, Response to Growth Hormone Stimulus