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FAS antibody (AA 81-170) (Cy5)

The Rabbit Polyclonal anti-FAS antibody has been validated for WB and FACS. It is suitable to detect FAS in samples from Human, Rat and Mouse.
Catalog No. ABIN1415387

Quick Overview for FAS antibody (AA 81-170) (Cy5) (ABIN1415387)

Target

See all FAS Antibodies
FAS (TNF Receptor Superfamily, Member 6 (FAS))

Reactivity

  • 248
  • 70
  • 63
  • 19
  • 6
  • 5
  • 5
  • 4
  • 2
  • 1
  • 1
Human, Rat, Mouse

Host

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  • 120
  • 3
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Rabbit

Clonality

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Polyclonal

Conjugate

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  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
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  • 1
  • 1
  • 1
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This FAS antibody is conjugated to Cy5

Application

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Western Blotting (WB), Flow Cytometry (FACS)
  • Binding Specificity

    • 24
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    • 16
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    • 8
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    AA 81-170

    Cross-Reactivity

    Human, Mouse, Rat

    Predicted Reactivity

    Pig

    Purification

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human FAS/Apo-1

    Isotype

    IgG
  • Application Notes

    FCM 1:20-100

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Expiry Date

    12 months
  • Target

    FAS (TNF Receptor Superfamily, Member 6 (FAS))

    Alternative Name

    Apo-1

    Background

    Synonyms: APT1, CD95, FAS1, APO-1, FASTM, ALPS1A, TNFRSF6, Tumor necrosis factor receptor superfamily member 6, Apo-1 antigen, Apoptosis-mediating surface antigen FAS, FASLG receptor, FAS

    Background: Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).

    Gene ID

    355

    UniProt

    P25445

    Pathways

    p53 Signaling, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
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