DPY19L1 antibody (AA 571-675) (Cy7)

Catalog No. ABIN1416104

The Rabbit Polyclonal anti-DPY19L1 antibody has been validated for WB, IF (cc) and IF (p). It is suitable to detect DPY19L1 in samples from Human.

Quick Overview for DPY19L1 antibody (AA 571-675) (Cy7) (ABIN1416104)

Target: DPY19L1 (Dpy-19-Like 1 (C. Elegans) (DPY19L1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DPY19L1 antibody is conjugated to Cy7

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-DPY19L1 Antibody (Cy7)

Binding Specificity: AA 571-675

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit,Zebrafish

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DPY19L1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for DPY19L1

Target: DPY19L1 (Dpy-19-Like 1 (C. Elegans) (DPY19L1))

Alternative Name: DPY19L1

Background:

Synonyms: D19L1_HUMAN, Dpy 19 like 1 C. elegans, Dpy 19 like protein 1, Dpy-19-like protein 1, DPY19L1, GA0500, KIAA0877, Protein dpy 19 homolog 1, Protein dpy-19 homolog 1, Protein dpy19 homolog 1.

Background: Dpy-19 (dumpy-19), is a 683 amino acid C. elegans protein that is required to orient the neuroblasts QL and QR correctly on the anterior/posterior axis. Dpy-19 is expressed highly in dorsal hyp7 cells, ventral P cells and lateral V cells, and dorsal and ventral body muscle cells. DPY19L1 (Dpy-19-like protein 1), also known as KIAA0877, is a 675 amino acid multi-pass membrane protein that belongs to the Dpy-19 family. DPY19L1 is expressed as two isoforms produced by alternative splicing and is encoded by a gene mapping to human chromosome 7, which encodes over 1,000 genes and makes up about 5 % of the human genome. Diseases associated with chromosome 7 include Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders including cases of acute myelogenous leukemia and myelodysplasia.

Gene ID: 23333

Pathways: SARS-CoV-2 Protein Interactome