SMEK2 antibody (AA 701-800) (Cy3)

Catalog No. ABIN1416311

The Rabbit Polyclonal anti-SMEK2 antibody is suitable to detect SMEK2 in samples from Human. It has been validated for WB, IF (cc) and IF (p).

Quick Overview for SMEK2 antibody (AA 701-800) (Cy3) (ABIN1416311)

Target: SMEK2 (SMEK Homolog 2, Suppressor of Mek1 (Dictyostelium) (SMEK2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMEK2 antibody is conjugated to Cy3

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-SMEK2 Antibody (Cy3)

Binding Specificity: AA 701-800

Purpose: PP4R3B Polyclonal Antibody, Cy3 Conjugated

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SMEK2/PP4R3B

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for SMEK2

Target: SMEK2 (SMEK Homolog 2, Suppressor of Mek1 (Dictyostelium) (SMEK2))

Alternative Name: PP4R3B

Background:

Synonyms: Protein Phosphatase 4, Regulatory Subunit 3 Beta, smk1, FLFL2, PPP4R3B, PSY2, Serine/threonine-protein phosphatase 4 regulatory subunit 3B, SMEK 2, SMEK homolog 2, SMEK homolog 2 suppressor of mek1 Dictyostelium, SMEK homolog 2 suppressor of mek1, FLJ31474, KIAA1387, PP4R3 beta, PP4R3B, PPP4R3 Beta, P4R3B_HUMAN.

Background: SMEK2 contains a WH1 domain. There are five named isoforms produced by alternative splicing. Mapping of a diet-induced hypercholesterolemia locus (Dihc2) in rats identified SMEK2 as a strong candidate for responsiveness to dietary cholesterol.

Gene ID: 57223

Pathways: Regulation of Carbohydrate Metabolic Process