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RTN4IP1 antibody (AA 111-210) (Cy5)

RTN4IP1 Reactivity: Mouse WB, IF (cc), IF (p) Host: Rabbit Polyclonal Cy5
Catalog No. ABIN1416348
  • Target See all RTN4IP1 Antibodies
    RTN4IP1 (Reticulon 4 Interacting Protein 1 (RTN4IP1))
    Binding Specificity
    • 14
    • 8
    • 8
    • 7
    • 5
    • 2
    • 1
    • 1
    • 1
    AA 111-210
    Reactivity
    • 33
    • 16
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Mouse
    Host
    • 44
    • 3
    Rabbit
    Clonality
    • 46
    • 1
    Polyclonal
    Conjugate
    • 14
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This RTN4IP1 antibody is conjugated to Cy5
    Application
    • 35
    • 20
    • 16
    • 14
    • 12
    • 12
    • 7
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Mouse
    Predicted Reactivity
    Human,Rat,Pig,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human NIMP/RTN4IP1
    Isotype
    IgG
    Top Product
    Discover our top product RTN4IP1 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    RTN4IP1 (Reticulon 4 Interacting Protein 1 (RTN4IP1))
    Alternative Name
    NIMP (RTN4IP1 Products)
    Synonyms
    RTN4IP1 antibody, NIMP antibody, D10Ertd690e antibody, RGD1563384 antibody, reticulon 4 interacting protein 1 antibody, RTN4IP1 antibody, Rtn4ip1 antibody
    Background

    Synonyms: mitochondrial, NIMP, NOGO interacting mitochondrial protein, NOGO-interacting mitochondrial protein, Reticulon 4 interacting protein 1, Reticulon 4 interacting protein 1, mitochondrial, Reticulon-4-interacting protein 1, RT4I1_HUMAN, Rtn4ip1, NIMP/RTN4IP1.

    Background: Appears to be a potent inhibitor of regeneration following spinal cord injury.Nogo is an oligodendrocyte-specific member of the Reticulon family and is a component of CNS white matter that inhibits axon outgrowth, induces collapse of growth cones of chick dorsal root ganglion cells, and inhibits the spreading of 3T3 fibroblasts. Nogo is expressed by oligodendrocytes but not by Schwann cells, and associates primarily with the endoplasmic reticulum. Nogo exists in three different splice forms, Nogo-A, -B and -C. NIMP (NOGO-interacting mitochondrial protein), also known as RTN4IP1 (Reticulon-4-interacting protein 1), is a 396 amino acid mitochondrial protein that contains a C-terminal oxidoreductaselike domain and numerous sites for phosphorylation. NIMP is expressed in mitochondrial-rich tissue such as kidney, heart, skeletal muscle and specific regions within the nervous system. Through interaction with Nogo, it is likely that NIMP plays a role in Nogo-induced inhibition of neurite growth. There are three isoforms of NIMP that are produced as a result of alternative splicing events.

    Gene ID
    84816
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