STING/TMEM173 antibody (AA 231-330) (Cy5)
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- Target See all STING/TMEM173 (TMEM173) Antibodies
- STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))
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Binding Specificity
- AA 231-330
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Reactivity
- Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This STING/TMEM173 antibody is conjugated to Cy5
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Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Rat
- Predicted Reactivity
- Human,Mouse,Dog,Cow,Pig,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human TMEM173
- Isotype
- IgG
- Top Product
- Discover our top product TMEM173 Primary Antibody
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anti-Transmembrane Protein 173 (TMEM173) (AA 159-373) antibody
TMEM173 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Transmembrane Protein 173 (TMEM173) antibodyTMEM173 Reactivity: Human WB, IHC, IHC (p) Host: Mouse Monoclonal 4H8 unconjugated
anti-Transmembrane Protein 173 (TMEM173) (AA 170-379) antibodyTMEM173 Reactivity: Human WB, IHC, IP, IF Host: Rabbit Polyclonal unconjugated
anti-Transmembrane Protein 173 (TMEM173) (AA 284-316), (C-Term) antibodyTMEM173 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Transmembrane Protein 173 (TMEM173) antibodyTMEM173 Reactivity: Mouse WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Transmembrane Protein 173 (TMEM173) (AA 311-340) antibodyTMEM173 Reactivity: Human WB, ELISA, IHC, FACS Host: Rabbit Polyclonal unconjugated
anti-Transmembrane Protein 173 (TMEM173) (AA 207-379) antibodyTMEM173 Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Transmembrane Protein 173 (TMEM173) (Internal Region) antibodyTMEM173 Reactivity: Human, Mouse, Rat WB, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Transmembrane Protein 173 (TMEM173) (AA 311-340), (C-Term) antibodyTMEM173 Reactivity: Human WB, FACS, IHC (p) Host: Rabbit Polyclonal RB25470 unconjugated
anti-Transmembrane Protein 173 (TMEM173) (C-Term) antibodyTMEM173 Reactivity: Human, Mouse WB, ELISA, IHC (p) Host: Rabbit Polyclonal unconjugated
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))
- Alternative Name
- TMEM173 (TMEM173 Products)
- Background
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Synonyms: Endoplasmic reticulum interferon stimulator, ERIS, hMITA, hSTING, Mediator of IRF3 activation, MITA, Mitochondrial mediator of IRF3 activation
Background: Facilitator of innate immune signaling that promotes the production of type I interferon (IFN-alpha and IFN-beta). Innate immune response is triggered in response to non-CpG double-stranded DNA from viruses and bacteria delivered to the cytoplasm. Able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon and exert a potent anti-viral state following expression. May be involved in translocon function, the translocon possibly being able to influence the induction of type I interferons. May be involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II). Mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway.
- Gene ID
- 340061
- UniProt
- Q86WV6
- Pathways
- Activation of Innate immune Response
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