UBE2G1 antibody (AA 101-170) (Cy7)
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- Target See all UBE2G1 (Ube2g1) Antibodies
- UBE2G1 (Ube2g1) (Ubiquitin-Conjugating Enzyme E2G 1 (Ube2g1))
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Binding Specificity
- AA 101-170
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Reactivity
- Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This UBE2G1 antibody is conjugated to Cy7
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Rat
- Predicted Reactivity
- Mouse,Dog,Sheep,Pig,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Ube2G1/UBC7
- Isotype
- IgG
- Top Product
- Discover our top product Ube2g1 Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- UBE2G1 (Ube2g1) (Ubiquitin-Conjugating Enzyme E2G 1 (Ube2g1))
- Alternative Name
- Ube2G1 (Ube2g1 Products)
- Synonyms
- E217K antibody, UBC7 antibody, UBE2G antibody, 2700059C12Rik antibody, AI256795 antibody, AU014992 antibody, AW552068 antibody, D130023C12Rik antibody, Ubc7 antibody, e217k antibody, ubc7 antibody, ube2g antibody, UB2G1 antibody, ube2g1 antibody, ubiquitin conjugating enzyme E2 G1 antibody, ubiquitin-conjugating enzyme E2G 1 antibody, ubiquitin-conjugating enzyme E2 G1 antibody, ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast) antibody, ubiquitin conjugating enzyme E2 G1 S homeolog antibody, UBE2G1 antibody, Ube2g1 antibody, EDI_082630 antibody, Bm1_26310 antibody, ube2g1 antibody, ube2g1.S antibody
- Background
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Synonyms: E217K, UB2G1_HUMAN, UBC 7, UBC7, UBC7 homolog yeast, UBE 2G, UBE2G, Ube2g1, Ubiquitin carrier protein G1, Ubiquitin conjugating enzyme E2 G1, Ubiquitin conjugating enzyme E2G 1 homologous to C. elegans UBC7, Ubiquitin conjugating enzyme E2G 1 UBC7 homolog C. elegans, Ubiquitin conjugating enzyme E2G 1 UBC7 homolog yeast, Ubiquitin conjugating enzyme E2G 1, Ubiquitin protein ligase G1, Ubiquitin-conjugating enzyme E2 G1, Ubiquitin-protein ligase G1.
Background: Ubiquitin is an abundant, highly conserved protein found in all eukaryotic cells either free or covalently attached to cellular proteins. The primary function of ubiquitin in mammalian systems is to clear abnormal, foreign, and improperly folded proteins by targeting them for proteosome degradation. In Saccharomyces cerevisiae, ubiquitin-like proteins include Rub1, Ula1, Uba3, Smt3, Ubc2, Ubc12 and Ubc9. Rub1 shares 53 % homology with ubiquitin and requires activation via the E2 proteins, including Ula1, Uba3 and Ubc12 in order to conjugate to substrates directed to different proteolytic systems. Ubc4 catalyzes ubiquitination of IkBa in a phosphorylation and SCFB-TRCP dependent manner. In this particular reaction, E1 first transfers ubiquitin to the E2 component Ubc4, and Ubc4 then associates with E3 ligase, which conjugates the poly-ubiquitin chain on a target protein. In this fashion, the chain tags the IkBa for degradation by a proteasome thus lifting the inhibitory effect of IkBa on NFkB and allowing NFkB to enter the nucleus.
- Gene ID
- 7326
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