Glutamate Receptor 1 antibody (pSer836) (HRP)

Catalog No. ABIN1417054

This Rabbit Polyclonal antibody specifically detects Glutamate Receptor 1 in ELISA. It exhibits reactivity toward Human.

Quick Overview for Glutamate Receptor 1 antibody (pSer836) (HRP) (ABIN1417054)

Target: Glutamate Receptor 1 (GLUR1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glutamate Receptor 1 antibody is conjugated to HRP

Application: ELISA

Product Details anti-Glutamate Receptor 1 Antibody (HRP)

Binding Specificity: pSer836

Predicted Reactivity: Human,Mouse,Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human GluR1 around the phosphorylation site of Ser836

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Gentamicin sulfate

Precaution of Use: This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Glutamate Receptor 1

Target: Glutamate Receptor 1 (GLUR1)

Alternative Name: GluR1

Background:

Synonyms: Glutamate Receptor 1 phospho S836, Glutamate Receptor 1 phospho Ser836, p-GluR1Ser836, p-GluR1r836, GLUR 1, GLUR A, AMPA 1, AMPA selective glutamate receptor 1, GLUH 1, GLUH1, GluR K1, GluR-1, GluR-A, GluR-K1, GLUR1, GLURA , GluRK1, Glutamate receptor 1, Glutamate receptor ionotropic AMPA 1, Gria 1, Gria1, Gria1, HBGR1, MGC133252, GRIA1_HUMAN.

Background: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Gene ID: 2890

Pathways: PI3K-Akt Signaling