FNDC5 antibody (AA 81-143) (Cy3)

Catalog No. ABIN1417187

The Rabbit Polyclonal anti-FNDC5 antibody is suitable to detect FNDC5 in samples from Human, Mouse and Rat. It has been validated for WB, IF (cc) and IF (p).

Quick Overview for FNDC5 antibody (AA 81-143) (Cy3) (ABIN1417187)

Target: FNDC5 (Fibronectin Type III Domain Containing 5 (FNDC5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FNDC5 antibody is conjugated to Cy3

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-FNDC5 Antibody (Cy3)

Binding Specificity: AA 81-143

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FNDC5 Irisin

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for FNDC5

Target: FNDC5 (Fibronectin Type III Domain Containing 5 (FNDC5))

Alternative Name: FNDC5

Background:

Synonyms: FRCP2, irisin, Fibronectin type III domain-containing protein 5, Fibronectin type III repeat-containing protein 2, FNDC5

Background: Irisin: Contrary to mouse, may not be involved in the beneficial effects of muscular exercise, nor in the induction of browning of human white adipose tissue.

Gene ID: 252995

UniProt: Q8NAU1

Pathways: Hormone Activity, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation