TPP1 antibody (AA 401-500) (Cy7)

Catalog No. ABIN1417442

The Rabbit Polyclonal anti-TPP1 antibody has been validated for WB, IF (cc) and IF (p). It is suitable to detect TPP1 in samples from Human and Mouse. There is 1 publication available.

Quick Overview for TPP1 antibody (AA 401-500) (Cy7) (ABIN1417442)

Target: TPP1 (Tripeptidyl Peptidase I (TPP1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TPP1 antibody is conjugated to Cy7

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-TPP1 Antibody (Cy7)

Binding Specificity: AA 401-500

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TPP1/CLN2

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

References for anti-TPP1 antibody (Cy7) (ABIN1417442)

Brenneman, Pearce, Kovacs, DeFrees: "Pharmacological Effects on Ceroid Lipofuscin and Neuronal Structure in Cln3∆ex7/8Mouse Brain Cultures." in: Journal of molecular neuroscience : MN, Vol. 63, Issue 1, pp. 100-114, (2017) (PubMed).

Target Details for TPP1

Target: TPP1 (Tripeptidyl Peptidase I (TPP1))

Alternative Name: TPP1

Background:

Synonyms: Cell growth inhibiting gene 1 protein, Cell growth-inhibiting gene 1 protein, Ceroid lipofuscinosis neuronal 2, Ceroid lipofuscinosis neuronal 2 late infantile Jansky Bielschowsky disease, Ceroid lipofuscinosis neuronal 2 late infantile antibody CLN 2, CLN2, CLN-2, GIG 1, GIG1, Growth inhibiting protein 1, LPIC, Lysosomal pepstatin insensitive protease, Lysosomal pepstatin-insensitive protease, TPP 1, TPP I, TPP-1, TPP-I, Tpp1, TPP1_HUMAN, TPPI, Tripeptidyl aminopeptidase, Tripeptidyl peptidase I, Tripeptidyl-peptidase 1, Tripeptidyl-peptidase I.

Background: Lysosomal serine protease with tripeptidyl-peptidase I activity. May act as a non-specific lysosomal peptidase which generates tripeptides from the breakdown products produced by lysosomal proteinases. Requires substrates with an unsubstituted N-terminus.

Gene ID: 1200

Pathways: Cell Division Cycle, ER-Nucleus Signaling